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The extreme variability and rapid evolution of Infectious bronchitis virus IBV has always represented the key challenge for its control because of the limited cross-protection among different strains. Several experimental trials have proven a broadening of the protection spectrum when animals are vaccinated with multiple genotypes. Nevertheless, the conditions of vaccine administration in field are so different that the generalization of experimental results is, at least, questionable.

In the present study a large scale epidemiological-phylodynamic approach was used to reconstruct the demographic history of the major field genotype i. These two countries were selected because, even if they share a comparable epidemiological scenario, the implemented vaccination protocols did not vary in Spain while changed dramatically in Italy over the time period considered.

One hundred and ninety-five Italian and 98 Spanish non-recombinant sequences of the hyper-variable region of the S1 gene obtained between and were analyzed using a serial coalescent-based approach to reconstruct viral population history over time. While the IBV QX population dynamics remained constant in Spain, a much more complex pattern was evidenced in Italy; both in terms of viral population size and clinical outbreak frequency.

Remarkably, a strong association with changes in vaccination strategies was recognized. Thus, a robust confirmation about the efficacy of IBV vaccination in field conditions was provided. Additionally, the history herein reported testifies the primary importance of rigorously planning not only the intervention strategies but also their monitoring and evaluation. Infectious bronchitis virus IBV represents one of the most relevant infectious diseases of poultry, causing severe economic losses mainly associated to respiratory and reproductive syndromes, decreased productive performances and increased mortality.

Even if biosecurity and good management practices are fundamental in the disease containment, widespread vaccination is also essential to control the disease.

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Has the era of king-size luxury SUVs come to an end? Check the second-gen QX New inside, new outside, new engine, new transmission, new chassis. So the QX56 continues as a body-on-frame design, but its Titan pickup foundation has been scrapped. The wheelbase is a couple inches shorter, at Oddly, for a vehicle with off-road credentials, minimum ground clearance has gone from Then again, off-road for most vehicles in this class is backing a trailer down a boat ramp.

The interior is distinguished by attractive design and excellent materials, with high marks for roominess, including the third-row seat. Go power has more appeal, too. Shared with the new M56 sedan, the V-8 engine— 5. But the new independent control-arm suspension is tuned to coddle, and it does this well.

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The pattern and rate of genome evolution have profound consequences in organismal evolution. Whole-genome duplication WGD , or polyploidy, has been recognized as an important evolutionary mechanism of plant diversification. However, in non-model plants the molecular signals of genome duplications have remained largely unexplored. High-throughput transcriptome data from next-generation sequencing have set the stage for novel investigations of genome evolution using new bioinformatic and methodological tools in a phylogenetic framework.

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Enter your email address and we’ll send you a link to reset your password. Enter last menstrual period LMP , current gestational age GA , OR expected due date to determine the other two, plus estimated date of conception. Please fill out required fields. Frank A. To view Dr. Chervenak’s publications, visit PubMed. This is an unprecedented time. It is the dedication of healthcare workers that will lead us through this crisis. Thank you for everything you do.

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Infiniti teases QX luxury SUV concept ahead of Beijing Auto Show

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If it rolls out as a full feature, you could hit Shuffle to watch something random, and hopefully strike streaming gold. Noise-cancelling, height channels and mics come as standard with JBL’s new range of gaming headsets. Do they deliver? Fancy a movie in your tent, or a binge on your bedroom wall? A virtually unknown brand packs budget wireless earbuds with tech and great sound — but are they too good to be true?

Thanks to a Microsoft blog, we now know what the Xbox Series X will look like when you boot it up According to one tech analyst, Google’s next flagship Pixel phone will drop at the end of next month, with the Pixel 4a 5G following soon after. We run the rule over two top Bluetooth speakers to see which wins for performance, features, price and build.

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